Minimizing embryo expulsion after embryo transfer: a randomized controlled study.
نویسنده
چکیده
BACKGROUND The aim of this work was to modify the embryo transfer technique to prevent expulsion of the embryos by exerting gentle mechanical pressure on the cervix using the vaginal speculum. METHODS A total of 639 infertile patients undergoing ICSI were prospectively randomized into two groups using sealed dark envelopes. In the study group (n=325) the screw of the vaginal speculum was loosened in order to exert a gentle pressure on the portiovaginalis of the cervix before ejecting the embryos, and was maintained for 7 min afterwards. In the control group (n=314) no pressure was applied on the cervix during embryo transfer and the vaginal speculum was removed after transferring the embryos. RESULTS The clinical pregnancy rate was significantly higher in the study group than in the control group [207/325 (67%) versus 150/314 (47.8%); odds ratio (OR) 1.39; 95% confidence interval (CI) 1.11-1.74]. The implantation rate was also significantly higher in the study group [304/913 (33.3%) versus 198/920 (21.5%); OR 1.54; 95% CI 1.26-1.89]. CONCLUSIONS Applying gentle mechanical pressure on the portiovaginalis of the cervix using the vaginal speculum during and after transferring the embryos significantly improved clinical pregnancy and implantation rates.
منابع مشابه
I-29: Can Fresh Embryo Transfers Be Replacedby Cryopreserved-Thawed Embryo Transfers inAssisted Reproductive Cycles? A RandomizedControlled Trial
Background: Controlled ovarian stimulation (COS) has been shown to advance endometrial maturation and affect adversely implantation in assisted reproduction technology (ART) cycles. It has been reported that there is a better embryo-endometrium synchrony in frozenthawed embryo transfer (FET) cycles than fresh embryo transfer (ET) cycles. The Background of this study was to compare ongoing pregn...
متن کاملEffect of Progesterone Supplementation on Natural Frozen-Thawed Embryo Transfer Cycles: A Randomized Controlled Trial
متن کامل
O-25: Single and Dual Embryo Transfer, HowFar We Are?
Background: To explore and compare the dual embryo transfer DET with single embryo transfer SET weather electively or not, in more viewpoints like financially, and scientifically and finding out which of these policies may give better outcome by analyzing both in a neutral broad spectrum manner. Materials and Methods: A computerized comprehensive search studies ended in finding of 62 articles o...
متن کاملP-203: The Impact of Low-Dose Aspirin on Clinical Reproductive Outcomes in Frozen- Thawed Embryo Transfer Cycles; A Randomized, Placebo-Controlled Double- Blind Study
Background: The objective of this study is to evaluate whether low-dose aspirin affects doppler sonographic parameters of the uterine arteries, endometrial thickness and pregnancy rate of women undergoing frozen-thawed embryo transfer cycles. Materials and Methods: This randomized, double- blind, placebo-controlled trial study was conducted between April 2012, and March 2013. A total of 60 elig...
متن کاملOnm-3: Embryo Transfer Performed by a Midwifein a Prospective Randomized Study
More than 15 % of couples have infertility problems. Thecauses of infertility are equally distributed among men and women. Assisted reproduction is an option which can help many of these couples. Because of ongoing research and development of the infertility treatments the pregnancy outcome after in vitro fertilization can be increased. Embryo transfer (ET) has in the Nordic countries, by tradi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Human reproduction
دوره 20 1 شماره
صفحات -
تاریخ انتشار 2005